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Striatal signaling regulated by the H3R histamine receptor in a mouse model of tic pathophysiology

Histamine dysregulation has been identified as a rare genetic cause of tic disorders; mice with a knockout of the histidine decarboxylase (Hdc) gene represent a promising model of this pathophysiology. How alterations in the histamine system lead to neuropsychiatric disease, however, remains unclear...

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Podrobná bibliografie
Vydáno v:Neuroscience
Hlavní autoři: Rapanelli, Maximiliano, Frick, Luciana, Jindachomthong, Kantiya, Xu, Jian, Ohtsu, Hiroshi, Nairn, Angus, Pittenger, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6204318/
https://ncbi.nlm.nih.gov/pubmed/30278251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2018.09.035
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