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The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons

The basal ganglia have a central role in motor patterning, habits, motivated behaviors, and cognition as well as in numerous neuropsychiatric disorders. Receptors for histamine, especially the H3 receptor (H3R), are highly expressed in the striatum, the primary input nucleus of the basal ganglia, bu...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Rapanelli, Maximiliano, Frick, Luciana R., Horn, Kyla D., Schwarcz, Rivka C., Pogorelov, Vladimir, Nairn, Angus C., Pittenger, Christopher
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076514/
https://ncbi.nlm.nih.gov/pubmed/27510032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731406
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