The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons

The basal ganglia have a central role in motor patterning, habits, motivated behaviors, and cognition as well as in numerous neuropsychiatric disorders. Receptors for histamine, especially the H3 receptor (H3R), are highly expressed in the striatum, the primary input nucleus of the basal ganglia, bu...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Rapanelli, Maximiliano, Frick, Luciana R., Horn, Kyla D., Schwarcz, Rivka C., Pogorelov, Vladimir, Nairn, Angus C., Pittenger, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076514/
https://ncbi.nlm.nih.gov/pubmed/27510032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.731406
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