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RNA pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD phosphorylation and transcriptional direction

Eukaryotic genes are marked by conserved post-translational modifications on the RNA pol II CTD and the chromatin template. How the 5′–3′ profiles of these marks are established is poorly understood. Using pol II mutants in human cells we found that slow transcription repositioned specific co-transc...

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Publicat a:Mol Cell
Autors principals: Fong, Nova, Saldi, Tassa, Sheridan, Ryan M., Cortazar, Michael A., Bentley, David L.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488731/
https://ncbi.nlm.nih.gov/pubmed/28506463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.04.016
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