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A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3′ end processing

The RNA polymerase II C-terminal heptad repeat domain (CTD) is essential for normal transcription and co-transcriptional processing of mRNA precursors. The mammalian CTD comprises 52 heptads whose consensus, YSPTSPS, is conserved throughout eukaryotes, followed by a 10 amino acid C-terminal sequence...

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Bibliografski detalji
Glavni autori: Fong, Nova, Bird, Gregory, Vigneron, Marc, Bentley, David L.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC175786/
https://ncbi.nlm.nih.gov/pubmed/12912924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg396
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