A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3′ end processing
The RNA polymerase II C-terminal heptad repeat domain (CTD) is essential for normal transcription and co-transcriptional processing of mRNA precursors. The mammalian CTD comprises 52 heptads whose consensus, YSPTSPS, is conserved throughout eukaryotes, followed by a 10 amino acid C-terminal sequence...
Shranjeno v:
| izdano v: | EMBO J |
|---|---|
| Principais autores: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Nature Publishing Group
2003
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg396 |
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