A 10 residue motif at the C-terminus of the RNA pol II CTD is required for transcription, splicing and 3′ end processing

The RNA polymerase II C-terminal heptad repeat domain (CTD) is essential for normal transcription and co-transcriptional processing of mRNA precursors. The mammalian CTD comprises 52 heptads whose consensus, YSPTSPS, is conserved throughout eukaryotes, followed by a 10 amino acid C-terminal sequence...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Fong, Nova, Bird, Gregory, Vigneron, Marc, Bentley, David L.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2003
Schlagworte:	Articles
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC175786/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12912924/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg396
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