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RNA pol II Dynamics Modulate Co-transcriptional Chromatin Modification, CTD phosphorylation and transcriptional direction

Eukaryotic genes are marked by conserved post-translational modifications on the RNA pol II CTD and the chromatin template. How the 5′–3′ profiles of these marks are established is poorly understood. Using pol II mutants in human cells we found that slow transcription repositioned specific co-transc...

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Détails bibliographiques
Publié dans:Mol Cell
Auteurs principaux: Fong, Nova, Saldi, Tassa, Sheridan, Ryan M., Cortazar, Michael A., Bentley, David L.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488731/
https://ncbi.nlm.nih.gov/pubmed/28506463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.04.016
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