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Protease-activated receptor-1 activation by granzyme B causes neurotoxicity that is augmented by interleukin-1β
BACKGROUND: The cause of neurodegeneration in progressive forms of multiple sclerosis is unknown. We investigated the impact of specific neuroinflammatory markers on human neurons to identify potential therapeutic targets for neuroprotection against chronic inflammation. METHODS: Surface immunocytoc...
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| 出版年: | J Neuroinflammation |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488439/ https://ncbi.nlm.nih.gov/pubmed/28655310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-0901-y |
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