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Modular Synthesis of Diverse Natural Product‐Like Macrocycles: Discovery of Hits with Antimycobacterial Activity
A modular synthetic approach was developed in which variation of the triplets of building blocks used enabled systematic variation of the macrocyclic scaffolds prepared. The approach was demonstrated in the synthesis of 17 diverse natural product‐like macrocyclic scaffolds of varied (12–20‐membered)...
Shranjeno v:
| izdano v: | Chemistry |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5488202/ https://ncbi.nlm.nih.gov/pubmed/28374952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201701150 |
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