Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

Toll-like receptors (TLRs) bind pathogen-specific ligands early in infection, initiating signaling pathways that lead to expression of multiple protective cellular genes. Many viruses have evolved strategies that block the effector mechanisms induced through these signaling pathways, but viral inter...

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Detalhes bibliográficos
Main Authors: Li, Kui, Foy, Eileen, Ferreon, Josephine C., Nakamura, Mitsuyasu, Ferreon, Allan C. M., Ikeda, Masanori, Ray, Stuart C., Gale, Michael, Lemon, Stanley M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548795/
https://ncbi.nlm.nih.gov/pubmed/15710891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408824102
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