The coxsackievirus B 3C protease cleaves MAVS and TRIF to attenuate host type I interferon and apoptotic signaling.
The host innate immune response to viral infections often involves the activation of parallel pattern recognition receptor (PRR) pathways that converge on the induction of type I interferons (IFNs). Several viruses have evolved sophisticated mechanisms to attenuate antiviral host signaling by direct...
Gorde:
| Egile Nagusiak: | , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science (PLoS)
2011-03-01
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| Saila: | PLoS Pathogens |
| Sarrera elektronikoa: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21436888/pdf/?tool=EBI |
| Etiketak: |
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