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Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF

Toll-like receptors (TLRs) bind pathogen-specific ligands early in infection, initiating signaling pathways that lead to expression of multiple protective cellular genes. Many viruses have evolved strategies that block the effector mechanisms induced through these signaling pathways, but viral inter...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Li, Kui, Foy, Eileen, Ferreon, Josephine C., Nakamura, Mitsuyasu, Ferreon, Allan C. M., Ikeda, Masanori, Ray, Stuart C., Gale, Michael, Lemon, Stanley M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548795/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15710891/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0408824102
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