The bromodomain inhibitor JQ1 triggers growth arrest and apoptosis in testicular germ cell tumours in vitro and in vivo

Type II testicular germ cell cancers (TGCT) are the most frequently diagnosed tumours in young men (20–40 years) and are classified as seminoma or non‐seminoma. TGCTs are commonly treated by orchiectomy and chemo‐ or radiotherapy. However, a subset of metastatic non‐seminomas (embryonal carcinomas)...

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Bibliografske podrobnosti
izdano v:J Cell Mol Med
Main Authors: Jostes, Sina, Nettersheim, Daniel, Fellermeyer, Martin, Schneider, Simon, Hafezi, François, Honecker, Friedemann, Schumacher, Valerie, Geyer, Matthias, Kristiansen, Glen, Schorle, Hubert
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487916/
https://ncbi.nlm.nih.gov/pubmed/28026145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13059
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