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Deciphering the molecular effects of romidepsin on germ cell tumours: DHRS2 is involved in cell cycle arrest but not apoptosis or induction of romidepsin effectors

Testicular germ cell tumours (GCTs) mostly affect young men at age 17‐40. Although high cure rates can be achieved by orchiectomy and chemotherapy, GCTs can still be a lethal threat to young patients with metastases or therapy resistance. Thus, alternative treatment options are needed. Based on stud...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Nettersheim, Daniel, Berger, Daniel, Jostes, Sina, Skowron, Margaretha, Schorle, Hubert
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307807/
https://ncbi.nlm.nih.gov/pubmed/30460772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13971
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