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Competitive Fitness of Fluconazole-Resistant Clinical Candida albicans Strains
The pathogenic yeast Candida albicans can develop resistance to the widely used antifungal agent fluconazole, which inhibits ergosterol biosynthesis. Resistance is often caused by gain-of-function mutations in the transcription factors Mrr1 and Tac1, which result in constitutive overexpression of mu...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487674/ https://ncbi.nlm.nih.gov/pubmed/28461316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00584-17 |
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