Immune Escape Variants of H9N2 Influenza Viruses Containing Deletions at the Hemagglutinin Receptor Binding Site Retain Fitness In Vivo and Display Enhanced Zoonotic Characteristics

H9N2 avian influenza viruses are enzootic in poultry across Asia and North Africa, where they pose a threat to human health as both zoonotic agents and potential pandemic candidates. Poultry vaccination against H9N2 viruses has been employed in many regions; however, vaccine effectiveness is frequen...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Peacock, Thomas P., Benton, Donald J., James, Joe, Sadeyen, Jean-Remy, Chang, Pengxiang, Sealy, Joshua E., Bryant, Juliet E., Martin, Stephen R., Shelton, Holly, Barclay, Wendy S., Iqbal, Munir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487547/
https://ncbi.nlm.nih.gov/pubmed/28468875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00218-17
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