Association of Increased Receptor-Binding Avidity of Influenza A(H9N2) Viruses with Escape from Antibody-Based Immunity and Enhanced Zoonotic Potential

We characterized 55 influenza A(H9N2) viruses isolated in Pakistan during 2014–2016 and found that the hemagglutinin gene is of the G1 lineage and that internal genes have differentiated into a variety of novel genotypes. Some isolates had up to 4-fold reduction in hemagglutination inhibition titers...

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Veröffentlicht in:Emerg Infect Dis
Hauptverfasser: Sealy, Joshua E., Yaqub, Tahir, Peacock, Thomas P., Chang, Pengxiang, Ermetal, Burcu, Clements, Anabel, Sadeyen, Jean-Remy, Mehboob, Arslan, Shelton, Holly, Bryant, Juliet E., Daniels, Rod S., McCauley, John W., Iqbal, Munir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Centers for Disease Control and Prevention 2019
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302589/
https://ncbi.nlm.nih.gov/pubmed/30561311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3201/eid2501.180616
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