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Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds

Brown adipocytes play an important role in human energy metabolism and prevention of obesity and diabetes. Induced pluripotent stem cells (iPSCs) represent a promising source for brown adipocytes; however, exogenous gene induction is generally required for iPSCs generation, which might cause undesir...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Takeda, Yukimasa, Harada, Yoshinori, Yoshikawa, Toshikazu, Dai, Ping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487346/
https://ncbi.nlm.nih.gov/pubmed/28655922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04665-x
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