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Highly efficient direct conversion of human fibroblasts to neuronal cells by chemical compounds

Direct conversion of mammalian fibroblasts into induced neuronal (iN) cells has been attained by forced expression of pro-neural transcriptional factors, or by combining defined factors with either microRNAs or small molecules. Here, we show that neuronal cells can be converted from postnatal human...

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Pubblicato in:J Clin Biochem Nutr
Autori principali: Dai, Ping, Harada, Yoshinori, Takamatsu, Tetsuro
Natura: Artigo
Lingua:Inglês
Pubblicazione: the Society for Free Radical Research Japan 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454078/
https://ncbi.nlm.nih.gov/pubmed/26060345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.15-39
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