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Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds

Brown adipocytes play an important role in human energy metabolism and prevention of obesity and diabetes. Induced pluripotent stem cells (iPSCs) represent a promising source for brown adipocytes; however, exogenous gene induction is generally required for iPSCs generation, which might cause undesir...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Takeda, Yukimasa, Harada, Yoshinori, Yoshikawa, Toshikazu, Dai, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5487346/
https://ncbi.nlm.nih.gov/pubmed/28655922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04665-x
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