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Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds
Brown adipocytes play an important role in human energy metabolism and prevention of obesity and diabetes. Induced pluripotent stem cells (iPSCs) represent a promising source for brown adipocytes; however, exogenous gene induction is generally required for iPSCs generation, which might cause undesir...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487346/ https://ncbi.nlm.nih.gov/pubmed/28655922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04665-x |
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