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A developed serum-free medium and an optimized chemical cocktail for direct conversion of human dermal fibroblasts into brown adipocytes

Brown adipocytes coordinate systemic energy metabolism associated with the pathogenesis of obesity and related metabolic diseases including type 2 diabetes. We have previously reported chemical compound-induced brown adipocytes (ciBAs) converted from human dermal fibroblasts without using transgenes...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Takeda, Yukimasa, Dai, Ping
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048747/
https://ncbi.nlm.nih.gov/pubmed/32111895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60769-x
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