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A developed serum-free medium and an optimized chemical cocktail for direct conversion of human dermal fibroblasts into brown adipocytes

Brown adipocytes coordinate systemic energy metabolism associated with the pathogenesis of obesity and related metabolic diseases including type 2 diabetes. We have previously reported chemical compound-induced brown adipocytes (ciBAs) converted from human dermal fibroblasts without using transgenes...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Takeda, Yukimasa, Dai, Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7048747/
https://ncbi.nlm.nih.gov/pubmed/32111895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60769-x
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