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Direct conversion of human fibroblasts to brown adipocytes by small chemical compounds
Brown adipocytes play an important role in human energy metabolism and prevention of obesity and diabetes. Induced pluripotent stem cells (iPSCs) represent a promising source for brown adipocytes; however, exogenous gene induction is generally required for iPSCs generation, which might cause undesir...
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| Publié dans: | Sci Rep |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5487346/ https://ncbi.nlm.nih.gov/pubmed/28655922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04665-x |
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