Direct conversion of human fibroblasts to dopaminergic neurons

Recent reports demonstrate that somatic mouse cells can be directly converted to other mature cell types by using combined expression of defined factors. Here we show that the same strategy can be applied to human embryonic and postnatal fibroblasts. By overexpression of the transcription factors As...

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Bibliografske podrobnosti
Main Authors: Pfisterer, Ulrich, Kirkeby, Agnete, Torper, Olof, Wood, James, Nelander, Jenny, Dufour, Audrey, Björklund, Anders, Lindvall, Olle, Jakobsson, Johan, Parmar, Malin
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121829/
https://ncbi.nlm.nih.gov/pubmed/21646515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105135108
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