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Direct conversion of human fibroblasts to dopaminergic neurons

Recent reports demonstrate that somatic mouse cells can be directly converted to other mature cell types by using combined expression of defined factors. Here we show that the same strategy can be applied to human embryonic and postnatal fibroblasts. By overexpression of the transcription factors As...

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Detalhes bibliográficos
Main Authors: Pfisterer, Ulrich, Kirkeby, Agnete, Torper, Olof, Wood, James, Nelander, Jenny, Dufour, Audrey, Björklund, Anders, Lindvall, Olle, Jakobsson, Johan, Parmar, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3121829/
https://ncbi.nlm.nih.gov/pubmed/21646515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105135108
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