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The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth
The long-term integrity of an articulating joint is dependent upon the nourishment of its cartilage component and the protection of the cartilage surface from friction-induced wear. Loss-of-function mutations in lubricin (a secreted glycoprotein encoded by the gene PRG4) cause the human autosomal re...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548698/ https://ncbi.nlm.nih.gov/pubmed/15719068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522263 |
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