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Cyclic loading increases friction and changes cartilage surface integrity in lubricin-mutant mouse knees
OBJECTIVE: To investigate the effects of lubricin gene dosage and cyclic loading on whole joint coefficient of friction and articular cartilage surface integrity in mouse knee joints. METHODS: Joints from mice with 2 (Prg4(+/+)), 1 (Prg4(+/−)), or no (Prg4(−/−)) functioning lubricin alleles were sub...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Wiley Subscription Services, Inc., A Wiley Company
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3252402/ https://ncbi.nlm.nih.gov/pubmed/21905020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.33337 |
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