Association between friction and wear in diarthrodial joints lacking lubricin

OBJECTIVE: The glycoprotein lubricin (encoded by the gene Prg4) is secreted by surface chondrocytes and synovial cells, and has been shown to reduce friction in vitro. In contrast to man-made bearings, mammalian diarthrodial joints must endogenously produce friction-reducing agents. This study was u...

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Detalhes bibliográficos
Main Authors: Jay, Gregory D, Torres, Jahn R, Rhee, David K, Helminen, Heikki J, Hytinnen, Mika M, Cha, Chung-Ja, Elsaid, Khaled, Kim, Kyung-Suk, Cui, Yajun, Warman, Matthew L
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2007
Assuntos:
Osteoarthritis Basic Science Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688668/
https://ncbi.nlm.nih.gov/pubmed/17968947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.22974
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