Parallel profiling of immune infiltrate subsets in uveal melanoma versus cutaneous melanoma unveils similarities and differences: A pilot study

The low response rates to immunotherapy in uveal melanoma (UM) sharply contrast with reputable response rates in cutaneous melanoma (CM) patients. To characterize the mechanisms responsible for resistance to immunotherapy in UM, we performed immune profiling in tumors from 10 metastatic UM patients...

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Pubblicato in:Oncoimmunology
Autori principali: Qin, Yong, Petaccia de Macedo, Mariana, Reuben, Alexandre, Forget, Marie-Andrée, Haymaker, Cara, Bernatchez, Chantale, Spencer, Christine N., Gopalakrishnan, Vancheswaran, Reddy, Sujan, Cooper, Zachary A., Fulbright, Orenthial J., Ramachandran, Renjith, Wahl, Arely, Flores, Esteban, Thorsen, Shawne T., Tavera, Rene J., Conrad, Claudius, Williams, Michelle D., Tetzlaff, Michael T., Wang, Wei-Lien, Gombos, Dan S., Esmaeli, Bita, Amaria, Rodabe N., Hwu, Patrick, Wargo, Jennifer A., Lazar, Alexander J., Patel, Sapna P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2017
Soggetti:
Brief Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486182/
https://ncbi.nlm.nih.gov/pubmed/28680759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1321187
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