A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes

Following the clinical success achieved with the first generation of adoptive cell therapy (ACT) utilizing in vitro expanded tumor-infiltrating lymphocytes (TILs), the second and third generations of TIL ACT are evolving toward the use of genetically modified TIL. TIL therapy generally involves the...

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Vydáno v:Front Immunol
Hlavní autoři: Forget, Marie-Andrée, Tavera, René J., Haymaker, Cara, Ramachandran, Renjith, Malu, Shuti, Zhang, Minying, Wardell, Seth, Fulbright, Orenthial J., Toth, Chistopher Leroy, Gonzalez, Audrey M., Thorsen, Shawne T., Flores, Esteban, Wahl, Arely, Peng, Weiyi, Amaria, Rodabe N., Hwu, Patrick, Bernatchez, Chantale
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539190/
https://ncbi.nlm.nih.gov/pubmed/28824634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00908
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