A Novel Method to Generate and Expand Clinical-Grade, Genetically Modified, Tumor-Infiltrating Lymphocytes

Following the clinical success achieved with the first generation of adoptive cell therapy (ACT) utilizing in vitro expanded tumor-infiltrating lymphocytes (TILs), the second and third generations of TIL ACT are evolving toward the use of genetically modified TIL. TIL therapy generally involves the...

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Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Forget, Marie-Andrée, Tavera, René J., Haymaker, Cara, Ramachandran, Renjith, Malu, Shuti, Zhang, Minying, Wardell, Seth, Fulbright, Orenthial J., Toth, Chistopher Leroy, Gonzalez, Audrey M., Thorsen, Shawne T., Flores, Esteban, Wahl, Arely, Peng, Weiyi, Amaria, Rodabe N., Hwu, Patrick, Bernatchez, Chantale
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5539190/
https://ncbi.nlm.nih.gov/pubmed/28824634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00908
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