Bispecific antibody does not induce T-cell death mediated by chimeric antigen receptor against disialoganglioside GD2

Chimeric antigen receptors (CAR) and bispecific antibodies (BsAb) are two powerful immunotherapy approaches for retargeting lymphocytes toward cancer cells. Despite their success in lymphoblastic leukemia, solid tumors have been more recalcitrant. Identifying therapeutic barriers facing CAR-modified...

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Foilsithe in:Oncoimmunology
Main Authors: Hoseini, Sayed Shahabuddin, Dobrenkov, Konstantin, Pankov, Dmitry, Xu, Xiaoliang L., Cheung, Nai-Kong V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2017
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486173/
https://ncbi.nlm.nih.gov/pubmed/28680755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320625
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