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Chimeric antigen receptors and bispecific antibodies to retarget T cells in pediatric oncology

Cancer immunotherapy using antigen-specific T cells has broad therapeutic potential. Chimeric antigen receptors and bispecific antibodies can redirect T cells to kill tumors without human leukocyte antigens (HLA) restriction. Key determinants of clinical potential include the choice of target antige...

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Detalhes bibliográficos
Publicado no:Pediatr Blood Cancer
Main Authors: Suzuki, Maya, Curran, Kevin J., Cheung, Nai-Kong V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976492/
https://ncbi.nlm.nih.gov/pubmed/25832831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pbc.25513
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