Bispecific antibody does not induce T-cell death mediated by chimeric antigen receptor against disialoganglioside GD2

Chimeric antigen receptors (CAR) and bispecific antibodies (BsAb) are two powerful immunotherapy approaches for retargeting lymphocytes toward cancer cells. Despite their success in lymphoblastic leukemia, solid tumors have been more recalcitrant. Identifying therapeutic barriers facing CAR-modified...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Hoseini, Sayed Shahabuddin, Dobrenkov, Konstantin, Pankov, Dmitry, Xu, Xiaoliang L., Cheung, Nai-Kong V.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486173/
https://ncbi.nlm.nih.gov/pubmed/28680755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1320625
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