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microRNA-29 mediates a novel negative feedback loop to regulate SCAP/SREBP-1 and lipid metabolism
The membrane-bound transcription factors, SREBPs (sterol regulatory element-binding proteins), play a central role in regulating lipid metabolism. The transcriptional activation of SREBPs requires the key protein SCAP (SREBP-cleavage activating protein) to translocate their precursors from the endop...
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| Publicado en: | RNA Dis |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5485916/ https://ncbi.nlm.nih.gov/pubmed/28664184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/rd.1525 |
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