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Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-driven Glioblastoma Growth

Dysregulated lipid metabolism is a characteristic of malignancies. Sterol regulatory element-binding protein-1 (SREBP-1), a transcription factor playing a central role in lipid metabolism, is highly activated in malignancies. Here, we unraveled a previously unappreciated link between miR-29 and the...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Ru, Peng, Hu, Peng, Geng, Feng, Mo, Xiaokui, Cheng, Chunming, Yoo, Ji Young, Cheng, Xiang, Wu, Xiaoning, Guo, Jeffrey Yunhua, Nakano, Ichiro, Lefai, Etienne, Kaur, Balveen, Chakravarti, Arnab, Guo, Deliang
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981543/
https://ncbi.nlm.nih.gov/pubmed/27477273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.017
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