Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-driven Glioblastoma Growth

Dysregulated lipid metabolism is a characteristic of malignancies. Sterol regulatory element-binding protein-1 (SREBP-1), a transcription factor playing a central role in lipid metabolism, is highly activated in malignancies. Here, we unraveled a previously unappreciated link between miR-29 and the...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ru, Peng, Hu, Peng, Geng, Feng, Mo, Xiaokui, Cheng, Chunming, Yoo, Ji Young, Cheng, Xiang, Wu, Xiaoning, Guo, Jeffrey Yunhua, Nakano, Ichiro, Lefai, Etienne, Kaur, Balveen, Chakravarti, Arnab, Guo, Deliang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981543/
https://ncbi.nlm.nih.gov/pubmed/27477273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.017
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