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SCAP links glucose to lipid metabolism in cancer cells

We recently revealed that glucose is a critical activator of sterol regulatory element-binding proteins (SREBPs) by promoting trafficking of SREBP-cleavage activating protein (SCAP)/SREBP complexes from the ER to the Golgi and subsequent SREBP activation via N-glycosylation of SCAP. Our study also d...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Autor principal: Guo, Deliang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822554/
https://ncbi.nlm.nih.gov/pubmed/27065222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1132120
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