A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory

The SNARE-mediated vesicular transport pathway plays major roles in synaptic remodeling associated with formation of long-term memories, but the mechanisms that regulate this pathway during memory acquisition are not fully understood. Here we identify miRNAs that are up-regulated in the rodent hippo...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Mathew, Rebecca S, Tatarakis, Antonis, Rudenko, Andrii, Johnson-Venkatesh, Erin M, Yang, Yawei J, Murphy, Elisabeth A, Todd, Travis P, Schepers, Scott T, Siuti, Nertila, Martorell, Anthony J, Falls, William A, Hammack, Sayamwong E, Walsh, Christopher A, Tsai, Li-Huei, Umemori, Hisashi, Bouton, Mark E, Moazed, Danesh
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293492/
https://ncbi.nlm.nih.gov/pubmed/28001126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.22467
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