PGC-1alpha Overexpression in Coronary Artery Disease Recruits Nitric Oxide and Hydrogen Peroxide during Flow-mediated Dilation and Protects Against Increased Intraluminal Pressure

Blood flow through healthy human vessels releases nitric oxide (NO) to produce vasodilation, whereas in patients with coronary artery disease (CAD), the mediator of dilation transitions to mitochondria-derived hydrogen peroxide ((mt)H(2)O(2)). Excessive (mt)H(2)O(2) production contributes to a proat...

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Detaylı Bibliyografya
Yayımlandı:Hypertension
Asıl Yazarlar: Kadlec, Andrew O., Chabowski, Dawid S., Ait-Aissa, Karima, Hockenberry, Joseph C., Otterson, Mary F., Durand, Matthew J., Freed, Julie K., Beyer, Andreas M., Gutterman, David D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485836/
https://ncbi.nlm.nih.gov/pubmed/28533333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09289
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