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PGC-1alpha Overexpression in Coronary Artery Disease Recruits Nitric Oxide and Hydrogen Peroxide during Flow-mediated Dilation and Protects Against Increased Intraluminal Pressure

Blood flow through healthy human vessels releases nitric oxide (NO) to produce vasodilation, whereas in patients with coronary artery disease (CAD), the mediator of dilation transitions to mitochondria-derived hydrogen peroxide ((mt)H(2)O(2)). Excessive (mt)H(2)O(2) production contributes to a proat...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Hypertension
Κύριοι συγγραφείς: Kadlec, Andrew O., Chabowski, Dawid S., Ait-Aissa, Karima, Hockenberry, Joseph C., Otterson, Mary F., Durand, Matthew J., Freed, Julie K., Beyer, Andreas M., Gutterman, David D.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2017
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485836/
https://ncbi.nlm.nih.gov/pubmed/28533333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09289
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