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The Role of PGC-1α in Vascular Regulation: Implications for Atherosclerosis

Mitochondrial dysfunction results in high levels of oxidative stress and mitochondrial damage, leading to disruption of endothelial homeostasis. Recent discoveries have clarified several pathways whereby mitochondrial dysregulation contributes to endothelial dysfunction and vascular disease burden....

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Kadlec, Andrew O., Chabowski, Dawid S., Ait-Aissa, Karima, Gutterman, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965312/
https://ncbi.nlm.nih.gov/pubmed/27312223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.307123
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