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Down-regulation of myasthenogenic T cell responses by a dual altered peptide ligand via CD4(+)CD25(+)-regulated events leading to apoptosis

The myasthenogenic peptides p195–212 and p259–271 are sequences of the human acetylcholine receptor and were shown to induce myasthenia gravis-associated immune responses in mice. A dual altered peptide ligand (APL) composed of the two APLs of the myasthenogenic peptides inhibited, in vitro and in v...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Ben-David, Hava, Sela, Michael, Mozes, Edna
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC548575/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15677327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409549102
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