Oral administration of a dual analog of two myasthenogenic T cell epitopes down-regulates experimental autoimmune myasthenia gravis in mice

Myasthenia gravis (MG) and experimental autoimmune MG (EAMG) are T cell-regulated, antibody-mediated autoimmune diseases. The major autoantigen in MG is the nicotinic acetylcholine receptor (AChR). Two peptides, representing sequences of the human AChR α-subunit, p195–212 and p259–271, were previous...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Paas-Rozner, Miri, Dayan, Molly, Paas, Yoav, Changeux, Jean-Pierre, Wirguin, Itzhak, Sela, Michael, Mozes, Edna
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681457/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.040554597
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