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Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis.

Myasthenia gravis is an autoimmune disease in which T cells specific to epitopes of the autoantigen, the human acetylcholine receptor, play a role. We identified two peptides, p195-212 and p259-271, from the alpha subunit of the receptor, which bound to major histocompatibility complex (MHC) class I...

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Detalhes bibliográficos
Main Authors: Zisman, E, Katz-Levy, Y, Dayan, M, Kirshner, S L, Paas-Rozner, M, Karni, A, Abramsky, O, Brautbar, C, Fridkin, M, Sela, M, Mozes, E
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC39566/
https://ncbi.nlm.nih.gov/pubmed/8633096
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