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Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis.

Myasthenia gravis is an autoimmune disease in which T cells specific to epitopes of the autoantigen, the human acetylcholine receptor, play a role. We identified two peptides, p195-212 and p259-271, from the alpha subunit of the receptor, which bound to major histocompatibility complex (MHC) class I...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Zisman, E, Katz-Levy, Y, Dayan, M, Kirshner, S L, Paas-Rozner, M, Karni, A, Abramsky, O, Brautbar, C, Fridkin, M, Sela, M, Mozes, E
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1996
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39566/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4492
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