Peptide analogs to pathogenic epitopes of the human acetylcholine receptor alpha subunit as potential modulators of myasthenia gravis.
Myasthenia gravis is an autoimmune disease in which T cells specific to epitopes of the autoantigen, the human acetylcholine receptor, play a role. We identified two peptides, p195-212 and p259-271, from the alpha subunit of the receptor, which bound to major histocompatibility complex (MHC) class I...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
1996
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39566/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4492 |
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