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Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4(+)CD25(+) regulatory cells
Myasthenia gravis is a T cell-dependent, antibody-mediated autoimmune disease. A dual altered peptide ligand (APL) that is composed of the tandemly arranged two single amino acid analogs of two myasthenogenic peptides, p195–212 and p259–271, was demonstrated to down-regulate in vitro and in vivo mya...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1177416/ https://ncbi.nlm.nih.gov/pubmed/16014414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504578102 |
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