Strain-specified characteristics of mouse synthetic prions

Synthetic prions were produced in our laboratory by using recombinant mouse prion protein (MoPrP) composed of residues 89-230. The first mouse synthetic prion strain (MoSP1) was inoculated into transgenic (Tg) 9949 mice expressing N-terminally truncated MoPrP(Δ23-88) and WT FVB mice expressing full-...

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Bibliografiske detaljer
Main Authors: Legname, Giuseppe, Nguyen, Hoang-Oanh B., Baskakov, Ilia V., Cohen, Fred E., DeArmond, Stephen J., Prusiner, Stanley B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC548557/
https://ncbi.nlm.nih.gov/pubmed/15671162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409079102
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