The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to Oncometabolites

Many enzymes make “mistakes”. Consequently, repair enzymes have evolved to correct these mistakes. For example, lactate dehydrogenase (LDH) and mitochondrial malate dehydrogenase (mMDH) slowly catalyze the reduction of 2-oxoglutarate (2-OG) to the oncometabolite l-2-hydroxyglutarate (l-2-HG). l-2-HG...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biology (Basel)
Egile Nagusiak: Hariharan, Vivek A., Denton, Travis T., Paraszcszak, Sarah, McEvoy, Kyle, Jeitner, Thomas M., Krasnikov, Boris F., Cooper, Arthur J. L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5485471/
https://ncbi.nlm.nih.gov/pubmed/28358347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology6020024
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak