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Reconstitution of intramembrane proteolysis in vitro reveals that pure rhomboid is sufficient for catalysis and specificity

Intramembrane proteolysis is a new paradigm in biology that controls signaling events throughout evolution. Hydrolysis of peptide bonds is thought to occur within the normally hydrophobic membrane environment, but insights into this unusual activity have been lacking because of difficulty in recapit...

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מידע ביבליוגרפי
Main Authors: Urban, Sinisa, Wolfe, Michael S.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC548546/
https://ncbi.nlm.nih.gov/pubmed/15684070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408306102
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