Structural and biochemical studies of human proliferating cell nuclear antigen complexes provide a rationale for cyclin association and inhibitor design

The interactions between the tumor suppressor protein p21(WAF1) and the cyclin-dependent kinase (CDK) complexes and with proliferating cell nuclear antigen (PCNA) regulate and coordinate the processes of cell-cycle progression and DNA replication. We present the x-ray crystal structure of PCNA compl...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kontopidis, George, Wu, Su-Ying, Zheleva, Daniella I., Taylor, Paul, McInnes, Campbell, Lane, David P., Fischer, Peter M., Walkinshaw, Malcolm D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC548533/
https://ncbi.nlm.nih.gov/pubmed/15681588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406540102
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados