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Ethanol Interactions with Dexmethylphenidate and dl-Methylphenidate Spheroidal Oral Drug Absorption Systems in Healthy Volunteers
BACKGROUND/PURPOSE: Ethanol co-administered with immediate-release dl-methylphenidate (dl-MPH) or dexmethylphenidate (d-MPH) significantly increases the geomean maximum plasma concentration (C(max)) of d-MPH 22% and 15%, respectively, and elevates overall drug exposure and psychostimulant effects. W...
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| Publicado no: | J Clin Psychopharmacol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5484776/ https://ncbi.nlm.nih.gov/pubmed/28590363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JCP.0000000000000721 |
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