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Absorption Differences between Immediate-Release Dexmethylphenidate and dl-Methylphenidate

The postulate that twice the milligram/kilogram dose of dl-methylphenidate (dl-MPH) would result in equal exposure to d-MPH compared with half that milligram/kilogram dose of the chiral switch product dexmethylphenidate (d-MPH) was tested. Using a randomized, crossover study design, 12 men and 12 wo...

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Detalhes bibliográficos
Publicado no:Drug Metab Dispos
Main Authors: Patrick, Kennerly S., Straughn, Arthur B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4767384/
https://ncbi.nlm.nih.gov/pubmed/26729760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.067975
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